JOINT TECHNOLOGY AND COLLABORATION AGREEMENT entered into as of the 4th day of

February 2000.







BETWEEN:    ARIDIA CORP., a corporation incorporated under the laws of the

            Province of Nova Scotia (hereinafter the "Corporation")





AND:        INFECTIO DIAGNOSTIC (I.D.I.) INC., a corporation incorporated under

            the laws of the Province of Quebec (hereinafter "IDI")





AND:        CEPHEID, a corporation incorporated under the laws of the state of

            California (hereinafter "Cepheid")







WHEREAS, IDI has expertise and know-how relating to certain nucleic acid

sequences for identification and diagnosis of certain human infectious disease

parameters as hereinafter described;



WHEREAS, Cepheid has expertise and know-how relating to systems, subsystems and

non-reagent consumables (such as disposable reaction tube), for diagnosing human

disease parameters;



WHEREAS IDI and Cepheid have granted to the Corporation exclusive licenses in

the Field relating to their respective technology;



WHEREAS IDI, Cepheid and the Corporation have entered into a Shareholders

Agreement dated February 4, 2000; and



WHEREAS IDI and Cepheid desire to cooperate in the discovery and development of

innovative diagnostic systems based on the integration of their respective

technologies;





NOW THEREFORE, in consideration of the mutual covenants and agreements

hereinafter set forth and other good and valuable consideration, the parties

hereby agree as follows:







{PAGE}   2

                                     - 2 -





                                    ARTICLE 1



                                   DEFINITIONS







As used in this agreement:



1.1   "AFFILIATE(s)" shall mean any corporation or other business entity

      controlled by or in common control of a party. "Control" as used herein

      means ownership directly or through one or more Affiliates, of fifty

      percent (50%) or more of the shares of stock entitled to vote for the

      election of directors, in the case of any corporation, or fifty percent

      (50%) or more of the equity interests in the case of any other type of

      legal entity, status as a general partner in any partnership, or any other

      arrangement whereby a party controls or has the right to control the board

      of directors or equivalent governing body of a corporation or other

      entity.



1.2   "CEPHEID" shall include all of the divisions, subsidiaries and Affiliates

      of Cepheid.



1.3   "CEPHEID INTELLECTUAL PROPERTY" shall mean all technology rights and

      patents rights (a) owned by Cepheid, existing as of the date hereof or

      developed subsequent to the date hereof and (b) relating to systems,

      subsystems and non reagent consumables for diagnosing human disease

      parameters including without limitations the patents and patents

      applications listed and described on Appendix A hereto. The Cepheid

      Intellectual Property shall also include any improvements, refinements,

      updates, discoveries or inventions related to Cepheid Intellectual

      Property and intellectual property developed by Cepheid in the course of

      the Collaboration Program.



1.4   "COLLABORATION PROGRAM" means any research program and associated

      activities contemplated by the parties during the term of this Agreement

      which program and activities shall, from time to time, be attached to this

      Agreement as Appendix B.



1.5   "COLLABORATIVE PRODUCTS" means any products which are discovered in whole

      or in part as a result of the Collaboration Program and made of Joint

      Technology.



1.6   "FIELD" shall mean the rapid diagnosis of human infectious diseases

      including but not limited to bacteria, fungi, antibiotic resistance and

      related disorders with systems integrating IDI Intellectual Property and

      Cepheid Intellectual Property.



1.7   "IDI" shall include all of the divisions, subsidiaries and Affiliates of

      IDI.



1.8   "IDI INTELLECTUAL PROPERTY" shall mean all technology rights and patent

      rights (a) owned by IDI, existing as of the date hereof or developed

      subsequent to the date hereof and (b) relating to nucleic acid sequences

      useful for the identification and/or diagnosis of human infectious disease

      parameters, including, without limitation, the patents and patent

      applications listed and described on Appendix C hereto. The IDI

      Intellectual Property shall also include any improvements, refinements,

      updates, discoveries or inventions related to IDI Intellectual Property

      and intellectual property developed by IDI in the course of the

      Collaboration Program.



1.9   "JOINT TECHNOLOGY" shall have the meaning ascribed to such term in section

      2.6.3. hereof.



1.10  "SHAREHOLDERS AGREEMENT" shall mean the Shareholders Agreement between

      IDI, Cepheid and the Corporation dated February 4, 2000, and any addenda

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